On-demand Webinar: Unlocking Single Cell Discovery in FFPE Tissues with CODEX
Recorded on Thursday, March 26, 2020
Speakers: Oliver Braubauch, PhD, Senior Applications Scientist, Akoya Biosciences
Abstract: The CODEX technology combines the advantages of modern single-cell omics technologies with those of conventional FFPE histology. CODEX can reveal 40+ biomarkers via an iterative antibody-oligo to oligo-fluorophore labeling strategy, in situ and at single cell resolution. The process is FFPE compatible, fully automated, budget-friendly and compactly enclosed in a benchtop unit. The rich data collected by CODEX enable cutting-edge, high-dimensionality biomarker analyses, including unbiased K-means clustering, interactive tSNE plotting and spatial network mapping. Collectively, CODEX allows users to interrogate complex phenotypic information about each cell within the context of spatial cellular interdependencies.
In this webinar we demonstrated how a 36 biomarker CODEX experiment was used to unlock discoveries in FFPE breast cancer tissue.
About the Speaker:
Oliver Braubach, PhD, received his doctorate from Dalhousie University in 2011. He then completed postdoctoral appointments at Yale and the Korea Institute of Science and Technology. During this time, he used state-of-the-art optical imaging and optogenetic technologies to investigate the structure and function of the nervous system. Oliver’s most recent academic appointment was at Cedars-Sinai where he conducted research in line with his background in optical imaging. It was during this time that Oliver started to use the CODEX® System and that he decided to follow his excitement for highly multiplexed imaging by joining Akoya. As a Senior Applications Scientist, Oliver has become the scientific evangelist for the CODEX workflow as he focuses his time on application development.