The Fastest Ultrahigh-Plex Panel for Immuno-Oncology Research

Curated from insights across 1,500+ publications and expertly designed to navigate the complexities of the Immuno-Oncology (IO) landscape, the PhenoCode IO60 Panel is the fastest ultrahigh-plex panel for IO research. When paired with the cutting-edge PhenoCycler®-Fusion 2.0, you can analyze 60 markers simultaneously and process over 16 samples per week.
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Comprehensive

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Fastest

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Scalable

Setting a New Standard for IO Research

Whether you’re looking to unlock the intricacies of the tumor microenvironment (TME), shed light on checkpoint therapy mechanisms, or drive breakthroughs in immunotherapy research, the PhenoCode™ Discovery IO60 Panel is a comprehensive, fast and scalable solution for ultrahigh-plex immune phenotyping—setting a new standard for IO research.

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What are the identities, composition and distribution of key immune cells within the TME?
What is the state of immune activation, suppression, and checkpoint regulation within the immune microenvironment?

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What is the state of immune activation, suppression, and checkpoint regulation within the immune microenvironment?
What are the structural and cellular characteristics of the tissue, and the state of the extracellular matrix?

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What are the activation states, polarization, and functional roles of myeloid cells, particularly macrophages and neutrophils?
Which cells are actively proliferating within the TME?

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What are the functional states, differentiation stages, and activation profiles of immune cells, including T cell exhaustion, regulatory function, and B cell maturation?
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Designed for Your Next IO Breakthrough

The PhenoCode IO60 Panel redefines IO research by offering a panoramic view of cancer biology, covering 90% of major immune cell types and 85% of key immune checkpoints. With 85% of known immunotherapy targets included, IO60 enables you to analyze immune cell diversity, assess checkpoint pathways, and understand immune evasion mechanisms—all critical factors in developing precision therapies and advancing immunotherapy.

Major Immune
Cell Types
 
90 %

Expose Tumors to Immune Detection by Targeting Evasion Mechanisms

Understand Tumor-Immune Interactions

Key Checkpoint
Inhibitors
 
85 %

Develop and Refine Checkpoint Inhibitors Therapies

Tailor Precision Medicine Approaches

Known
Immunotherapy
Targets
85 %

Drive Therapies to Boost Anti-Tumor Responses and Suppress Pro-Tumor Activity

Accelerate Immunotherapy Research

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Speed Up Your Spatial Discoveries with the IO60 Panel

Fully Optimized

Achieve in days what once took weeks.

Ready-to-use and off-the-shelf, the IO60 Panel is fully optimized to save you valuable time in assay development.

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High Speed

Drive breakthroughs with faster, smarter decisions.

The IO60 Panel is designed for the PhenoCycler-Fusion 2.0, which features automated fluidics and patented height-sensing optics to enable rapid, comprehensive tumor phenotyping.

High Throughput

Stay ahead by analyzing mores samples, faster.

With the IO60 Panel on the PhenoCycler-Fusion 2.0, process 16+ samples per week at 60-plex using multi-slide automation and parallel processing to keep your research on the cutting edge.

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Scale Up Your IO Insights with the IO60 Panel

Make impactful discoveries across virtually any cancer type

From solid tumors like lung and colon cancer to blood cancers like leukemia, the IO60 Panel provides powerful insights across 10+ major cancer types.
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Understand each pathway across every step of cancer progression

From immune checkpoints and T cell activation to antigen presentation, TME dynamics and cell proliferation, the IO60 panel targets 9 critical pathways across cancer immunity cycle and more.

Expand insights and deepen research possibilities

With a 60-marker base scalable to a 100-plex using additional barcodes, the IO60 antibody panel opens doors to expanded insights and deeper research possibilities.

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PhenoCode
IO60

A Simplified End-to-end Workflow for Ultrahigh-Plex Spatial Phenotyping

Stain

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PhenoCode IO60 Panel

Image

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Automated Cycling and Imaging

Analyze

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Image Analysis

Integrate

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Multimodal Phenotyping

Interested in learning more?

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