Quantifying Tumor Heterogeneity and Mapping Complex Immune Cell Interactions with High-Throughput, 7-Color Multispectral Slide Scans

We build upon our previous Phenoptics™ (rebranded as PhenoImager) platform advancements and demonstrate that, using our Opal™ 6-plex, 7-color fluorophores and the Vectra Polaris (rebranded as PhenoImager HT), spatial measurements can now be revealed using this high-throughput, translational workflow, including distance between nearest cell neighbors to the extent of the invasive margin.