Publications

Prognostic significance of myeloid immune cells and their spatial distribution in the colorectal cancer microenvironment

Väyrynen, J. P., Haruki, K., Väyrynen, S. A., Lau, M. C., Costa, A. D., Borowsky, J., … & Nowak, J. A. (2021). Prognostic significance of myeloid immune cells and their spatial distribution in the colorectal cancer microenvironment. Journal for immunotherapy of cancer, 9(4).

Prognostic significance of myeloid immune cells and their spatial distribution in the colorectal cancer microenvironment Read More »

Tumor cell PD-L1 expression is a strong predictor of unfavorable prognosis in immune checkpoint therapy-naive clear cell renal cell cancer

Möller, K., Fraune, C., Blessin, N. C., Lennartz, M., Kluth, M., Hube-Magg, C., Lindhorst, L., Dahlem, R., Fisch, M., Eichenauer, T., Riechardt, S., Simon, R., Sauter, G., Büscheck, F., Höppner, W., Matthies, C., Doh, O., Krech, T., Marx, A. H., Zecha, H., … Clauditz, T. S. (2021). Tumor cell PD-L1 expression is a strong predictor of unfavorable prognosis in immune checkpoint therapy-naive clear cell renal cell cancer. International urology and nephrology, 10.1007/s11255-021-02841-7. Advance online publication. https://doi.org/10.1007/s11255-021-02841-7

Tumor cell PD-L1 expression is a strong predictor of unfavorable prognosis in immune checkpoint therapy-naive clear cell renal cell cancer Read More »

Inhibition of STAT3 augments antitumor efficacy of anti-CTLA-4 treatment against prostate cancer

Witt, K., Evans-Axelsson, S., Lundqvist, A., Johansson, M., Bjartell, A., & Hellsten, R. (2021). Inhibition of STAT3 augments antitumor efficacy of anti-CTLA-4 treatment against prostate cancer. Cancer immunology, immunotherapy : CII, 10.1007/s00262-021-02915-6. Advance online publication. https://doi.org/10.1007/s00262-021-02915-6

Inhibition of STAT3 augments antitumor efficacy of anti-CTLA-4 treatment against prostate cancer Read More »

ARG1 mRNA Level Is a Promising Prognostic Marker in Head and Neck Squamous Cell Carcinomas

Pokrývková, B., Šmahelová, J., Dalewská, N., Grega, M., Vencálek, O., Šmahel, M., Nunvář, J., Klozar, J., & Tachezy, R. (2021). ARG1 mRNA Level Is a Promising Prognostic Marker in Head and Neck Squamous Cell Carcinomas. Diagnostics (Basel, Switzerland), 11(4), 628. https://doi.org/10.3390/diagnostics11040628

ARG1 mRNA Level Is a Promising Prognostic Marker in Head and Neck Squamous Cell Carcinomas Read More »

Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature

Ingelfinger, F., Krishnarajah, S., Kramer, M., Utz, S. G., Galli, E., Lutz, M., Zwicky, P., Akarca, A. U., Jurado, N. P., Ulutekin, C., Bamert, D., Widmer, C. C., Piccoli, L., Sallusto, F., Núñez, N. G., Marafioti, T., Schneiter, D., Opitz, I., Lanzavecchia, A., Jung, H. H., … Becher, B. (2021). Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta neuropathologica, 141(6), 901–915. https://doi.org/10.1007/s00401-021-02299-y

Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature Read More »

Mutation in the Ciliary Protein C2CD3 Reveals Organ-Specific Mechanisms of Hedgehog Signal Transduction in Avian Embryos

Brooks, E. C., Bonatto Paese, C. L., Carroll, A. H., Struve, J. N., Nagy, N., & Brugmann, S. A. (2021). Mutation in the Ciliary Protein C2CD3 Reveals Organ-Specific Mechanisms of Hedgehog Signal Transduction in Avian Embryos. Journal of developmental biology, 9(2), 12. https://doi.org/10.3390/jdb9020012

Mutation in the Ciliary Protein C2CD3 Reveals Organ-Specific Mechanisms of Hedgehog Signal Transduction in Avian Embryos Read More »

Hyaluronan is a natural and effective immunological adjuvant for protein-based vaccines

Dalla Pietà, A., Carpanese, D., Grigoletto, A., Tosi, A., Dalla Santa, S., Pedersen, G. K., Christensen, D., Meléndez-Alafort, L., Barbieri, V., De Benedictis, P., Pasut, G., Montagner, I. M., & Rosato, A. (2021). Hyaluronan is a natural and effective immunological adjuvant for protein-based vaccines. Cellular & molecular immunology, 18(5), 1197–1210. https://doi.org/10.1038/s41423-021-00667-y

Hyaluronan is a natural and effective immunological adjuvant for protein-based vaccines Read More »

Tumor-infiltrating plasmacytoid dendritic cells are associated with survival in human colon cancer

Kießler, M., Plesca, I., Sommer, U., Wehner, R., Wilczkowski, F., Müller, L., Tunger, A., Lai, X., Rentsch, A., Peuker, K., Zeissig, S., Seifert, A. M., Seifert, L., Weitz, J., Bachmann, M., Bornhäuser, M., Aust, D., Baretton, G., & Schmitz, M. (2021). Tumor-infiltrating plasmacytoid dendritic cells are associated with survival in human colon cancer. Journal for immunotherapy of cancer, 9(3), e001813. https://doi.org/10.1136/jitc-2020-001813

Tumor-infiltrating plasmacytoid dendritic cells are associated with survival in human colon cancer Read More »

Cathepsin B and D deficiency in the mouse pancreas induces impaired autophagy and chronic pancreatitis

Iwama, H., Mehanna, S., Imasaka, M., Hashidume, S., Nishiura, H., Yamamura, K. I., Suzuki, C., Uchiyama, Y., Hatano, E., & Ohmuraya, M. (2021). Cathepsin B and D deficiency in the mouse pancreas induces impaired autophagy and chronic pancreatitis. Scientific reports, 11(1), 6596. https://doi.org/10.1038/s41598-021-85898-9

Cathepsin B and D deficiency in the mouse pancreas induces impaired autophagy and chronic pancreatitis Read More »