Publications

The immune suppressive microenvironment affects efficacy of radio‐immunotherapy in brain metastasis

Niesel, K., Schulz, M., Anthes, J., Alekseeva, T., Macas, J., Salamero-Boix, A., Möckl, A., Oberwahrenbrock, T., Lolies, M., Stein, S., Plate, K. H., Reiss, Y., Rödel, F., & Sevenich, L. (2021). The immune suppressive microenvironment affects efficacy of radio-immunotherapy in brain metastasis. EMBO molecular medicine, 13(5), e13412. https://doi.org/10.15252/emmm.202013412

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Prurigo Nodularis is Characterized by Systemic and Cutaneous Th22 Immune Polarization

Belzberg, M., Alphonse, M. P., Brown, I., Williams, K. A., Khanna, R., Ho, B., Wongvibulsin, S., Pritchard, T., Roh, Y. S., Sutaria, N., Choi, J., Jedrych, J., Johnston, A. D., Sarkar, K., Vasavda, C., Meixiong, J., Dillen, C., Bondesgaard, K., Paolini, J. F., Chen, W., … Kwatra, S. G. (2021). Prurigo Nodularis Is Characterized by Systemic and Cutaneous T Helper 22 Immune Polarization. The Journal of investigative dermatology, S0022-202X(21)01016-2. Advance online publication. https://doi.org/10.1016/j.jid.2021.02.749

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Single-cell RNA sequencing of human liver reveals hepatic stellate cell heterogeneity

Payen, V. L., Lavergne, A., Alevra Sarika, N., Colonval, M., Karim, L., Deckers, M., Najimi, M., Coppieters, W., Charloteaux, B., Sokal, E. M., & El Taghdouini, A. (2021). Single-cell RNA sequencing of human liver reveals hepatic stellate cell heterogeneity. JHEP reports : innovation in hepatology, 3(3), 100278. https://doi.org/10.1016/j.jhepr.2021.100278

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Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment

Zhang, M., Luo, J. L., Sun, Q., Harber, J., Dawson, A. G., Nakas, A., Busacca, S., Sharkey, A. J., Waller, D., Sheaff, M. T., Richards, C., Wells-Jordan, P., Gaba, A., Poile, C., Baitei, E. Y., Bzura, A., Dzialo, J., Jama, M., Le Quesne, J., Bajaj, A., … Fennell, D. A. (2021). Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment. Nature communications, 12(1), 1751. https://doi.org/10.1038/s41467-021-21798-w

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Persistent repression of tau in the brain using engineered zinc finger protein transcription factors

Wegmann, S., DeVos, S. L., Zeitler, B., Marlen, K., Bennett, R. E., Perez-Rando, M., MacKenzie, D., Yu, Q., Commins, C., Bannon, R. N., Corjuc, B. T., Chase, A., Diez, L., Nguyen, H. B., Hinkley, S., Zhang, L., Goodwin, A., Ledeboer, A., Lam, S., Ankoudinova, I., … Hyman, B. T. (2021). Persistent repression of tau in the brain using engineered zinc finger protein transcription factors. Science advances, 7(12), eabe1611. https://doi.org/10.1126/sciadv.abe1611

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Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer

Tanyi, J. L., Chiang, C. L., Chiffelle, J., Thierry, A. C., Baumgartener, P., Huber, F., Goepfert, C., Tarussio, D., Tissot, S., Torigian, D. A., Nisenbaum, H. L., Stevenson, B. J., Guiren, H. F., Ahmed, R., Huguenin-Bergenat, A. L., Zsiros, E., Bassani-Sternberg, M., Mick, R., Powell, D. J., Jr, Coukos, G., … Kandalaft, L. E. (2021). Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer. NPJ vaccines, 6(1), 36. https://doi.org/10.1038/s41541-021-00297-5

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LAG-3-Expressing Tumor-Infiltrating T Cells Are Associated with Reduced Disease-Free Survival in Pancreatic Cancer

Seifert, L., Plesca, I., Müller, L., Sommer, U., Heiduk, M., von Renesse, J., Digomann, D., Glück, J., Klimova, A., Weitz, J., Schmitz, M., & Seifert, A. M. (2021). LAG-3-Expressing Tumor-Infiltrating T Cells Are Associated with Reduced Disease-Free Survival in Pancreatic Cancer. Cancers, 13(6), 1297. https://doi.org/10.3390/cancers13061297

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Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

Butler, D., Mozsary, C., Meydan, C., Foox, J., Rosiene, J., Shaiber, A., Danko, D., Afshinnekoo, E., MacKay, M., Sedlazeck, F. J., Ivanov, N. A., Sierra, M., Pohle, D., Zietz, M., Gisladottir, U., Ramlall, V., Sholle, E. T., Schenck, E. J., Westover, C. D., Hassan, C., … Mason, C. E. (2021). Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions. Nature communications, 12(1), 1660. https://doi.org/10.1038/s41467-021-21361-7

Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions Read More »