Publications

Identification of distinct immune landscapes using an automated nine-color multiplex immunofluorescence staining panel and image analysis in paraffin tumor tissues

Parra, E. R., Zhai, J., Tamegnon, A., Zhou, N., Pandurengan, R. K., Barreto, C., Jiang, M., Rice, D. C., Creasy, C., Vaporciyan, A. A., Hofstetter, W. L., Tsao, A. S., Wistuba, I. I., Sepesi, B., & Haymaker, C. (2021). Identification of distinct immune landscapes using an automated nine-color multiplex immunofluorescence staining panel and image analysis in paraffin tumor tissues. Scientific reports, 11(1), 4530. https://doi.org/10.1038/s41598-021-83858-x

Identification of distinct immune landscapes using an automated nine-color multiplex immunofluorescence staining panel and image analysis in paraffin tumor tissues Read More »

Association of Fusobacterium nucleatum with Specific T Cell Subsets in the Colorectal Carcinoma Microenvironment

Borowsky, J., Haruki, K., Lau, M. C., Dias Costa, A., Väyrynen, J. P., Ugai, T., Arima, K., da Silva, A., Felt, K. D., Zhao, M., Gurjao, C., Twombly, T. S., Fujiyoshi, K., Väyrynen, S. A., Hamada, T., Mima, K., Bullman, S., Harrison, T. A., Phipps, A. I., Peters, U., … Ogino, S. (2021). Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment. Clinical cancer research : an official journal of the American Association for Cancer Research, 27(10), 2816–2826. https://doi.org/10.1158/1078-0432.CCR-20-4009

Association of Fusobacterium nucleatum with Specific T Cell Subsets in the Colorectal Carcinoma Microenvironment Read More »

Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9

Rodriguez, E., Boelaars, K., Brown, K., Li, R. E., Kruijssen, L., Bruijns, S. C., … & van Kooyk, Y. (2021). Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9. Nature communications, 12(1), 1-14.

Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9 Read More »

Enhancement of liver-directed transgene expression at initial and repeat doses of AAV vectors admixed with ImmTOR nanoparticles

Ilyinskii, P. O., Michaud, A. M., Roy, C. J., Rizzo, G. L., Elkins, S. L., Capela, T., Chowdhury, A. C., Leung, S. S., & Kishimoto, T. K. (2021). Enhancement of liver-directed transgene expression at initial and repeat doses of AAV vectors admixed with ImmTOR nanoparticles. Science advances, 7(9), eabd0321. https://doi.org/10.1126/sciadv.abd0321

Enhancement of liver-directed transgene expression at initial and repeat doses of AAV vectors admixed with ImmTOR nanoparticles Read More »

Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients

Zhao, Y., Kilian, C., Turner, J. E., Bosurgi, L., Roedl, K., Bartsch, P., Gnirck, A. C., Cortesi, F., Schultheiß, C., Hellmig, M., Enk, L., Hausmann, F., Borchers, A., Wong, M. N., Paust, H. J., Siracusa, F., Scheibel, N., Herrmann, M., Rosati, E., Bacher, P., … Krebs, C. F. (2021). Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients. Science immunology, 6(56), eabf6692. https://doi.org/10.1126/sciimmunol.abf6692

Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients Read More »

Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer–T cell coculture models

Mimura, K., Kua, L. F., Xiao, J. F., Asuncion, B. R., Nakayama, Y., Syn, N., Fazreen, Z., Soong, R., Kono, K., & Yong, W. P. (2021). Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer-T cell coculture models. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 24(3), 611–623. https://doi.org/10.1007/s10120-020-01151-8

Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer–T cell coculture models Read More »