Publications Archive - Page 29 of 50

Differences in TCR repertoire and T cell activation underlie the divergent outcomes of antitumor immune responses in tumor-eradicating versus tumor-progressing hosts

Woolaver, R. A., Wang, X., Krinsky, A. L., Waschke, B. C., Chen, S., Popolizio, V., Nicklawsky, A. G., Gao, D., Chen, Z., Jimeno, A., Wang, X. J., & Wang, J. H. (2021). Differences in TCR repertoire and T cell activation underlie the divergent outcomes of antitumor immune responses in tumor-eradicating versus tumor-progressing hosts. Journal for immunotherapy of cancer, 9(1), e001615. https://doi.org/10.1136/jitc-2020-001615

Differences in TCR repertoire and T cell activation underlie the divergent outcomes of antitumor immune responses in tumor-eradicating versus tumor-progressing hosts Read More »

Altered Spatial Composition of the Immune Cell Repertoire in Association to CD34+ Blasts in Myelodysplastic Syndromes and Secondary Acute Myeloid Leukemia

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Bauer, M., Vaxevanis, C., Al-Ali, H. K., Jaekel, N., Naumann, C., Schaffrath, J., Rau, A., Seliger, B., & Wickenhauser, C. (2021). Altered Spatial Composition of the Immune Cell Repertoire in Association to CD34+ Blasts in Myelodysplastic Syndromes and Secondary Acute Myeloid Leukemia. Cancers, 13(2), 186. https://doi.org/10.3390/cancers13020186

Altered Spatial Composition of the Immune Cell Repertoire in Association to CD34+ Blasts in Myelodysplastic Syndromes and Secondary Acute Myeloid Leukemia Read More »

Gut-licensed IFNγ + NK cells drive LAMP1 + TRAIL + anti-inflammatory astrocytes

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Sanmarco, L. M., Wheeler, M. A., Gutiérrez-Vázquez, C., Polonio, C. M., Linnerbauer, M., Pinho-Ribeiro, F. A., Li, Z., Giovannoni, F., Batterman, K. V., Scalisi, G., Zandee, S., Heck, E. S., Alsuwailm, M., Rosene, D. L., Becher, B., Chiu, I. M., Prat, A., & Quintana, F. J. (2021). Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes. Nature, 590(7846), 473–479. https://doi.org/10.1038/s41586-020-03116-4

Gut-licensed IFNγ + NK cells drive LAMP1 + TRAIL + anti-inflammatory astrocytes Read More »

LncRNA DANCR represses Doxorubicin-induced apoptosis through stabilizing MALAT1 expression in colorectal cancer cells

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Xiong, M., Wu, M., Dan Peng, Huang, W., Chen, Z., Ke, H., Chen, Z., Song, W., Zhao, Y., Xiang, A. P., & Zhong, X. (2021). LncRNA DANCR represses Doxorubicin-induced apoptosis through stabilizing MALAT1 expression in colorectal cancer cells. Cell death & disease, 12(1), 24. https://doi.org/10.1038/s41419-020-03318-8

LncRNA DANCR represses Doxorubicin-induced apoptosis through stabilizing MALAT1 expression in colorectal cancer cells Read More »

Insulin Receptor Substrate p53 Ameliorates High-Glucose-Induced Activation of NF-κB and Impaired Mobility of HUVECs

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Liu, F., Chen, Y., Zhao, S., Li, M., Luo, F., & Tang, C. E. (2021). Insulin Receptor Substrate p53 Ameliorates High-Glucose-Induced Activation of NF-κB and Impaired Mobility of HUVECs. BioMed research international, 2021, 3210586. https://doi.org/10.1155/2021/3210586

Insulin Receptor Substrate p53 Ameliorates High-Glucose-Induced Activation of NF-κB and Impaired Mobility of HUVECs Read More »

The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes

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Salas-Benito, D., Conde, E., Tamayo-Uria, I., Mancheño, U., Elizalde, E., Garcia-Ros, D., Aramendia, J. M., Muruzabal, J. C., Alcaide, J., Guillen-Grima, F., Minguez, J. A., Amores-Tirado, J., Gonzalez-Martin, A., Sarobe, P., Lasarte, J. J., Ponz-Sarvise, M., De Andrea, C. E., & Hervas-Stubbs, S. (2021). The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes. British journal of cancer, 124(6), 1138–1149. https://doi.org/10.1038/s41416-020-01218-4

The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes Read More »

Rova-T Enhances the Anti-Tumor Activity of Anti-PD1 in a Murine Model of Small Cell Lung Cancer with Endogenous Dll3 Expression

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Vitorino, P., Chuang, C. H., Iannello, A., Zhao, X., Anderson, W., Ferrando, R., … & Saunders, L. R. (2021). Rova-T enhances the anti-tumor activity of anti-PD1 in a murine model of small cell lung cancer with endogenous Dll3 expression. Translational oncology, 14(1), 100883.

Rova-T Enhances the Anti-Tumor Activity of Anti-PD1 in a Murine Model of Small Cell Lung Cancer with Endogenous Dll3 Expression Read More »

Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis

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Chiavarina, B., Costanza, B., Ronca, R., Blomme, A., Rezzola, S., Chiodelli, P., Giguelay, A., Belthier, G., Doumont, G., Van Simaeys, G., Lacroix, S., Yokobori, T., Erkhem-Ochir, B., Balaguer, P., Cavailles, V., Fabbrizio, E., Di Valentin, E., Gofflot, S., Detry, O., Jerusalem, G., … Turtoi, A. (2021). Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis. Theranostics, 11(4), 1626–1640. https://doi.org/10.7150/thno.51507

Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis Read More »

Commensal-Driven Immune Zonation of the Liver Promotes Host Defence

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Gola, A., Dorrington, M. G., Speranza, E., Sala, C., Shih, R. M., Radtke, A. J., … & Germain, R. N. (2021). Commensal-driven immune zonation of the liver promotes host defence. Nature, 589(7840), 131-136.

Commensal-Driven Immune Zonation of the Liver Promotes Host Defence Read More »

PD-L1 Multiplex and Quantitative Image Analysis for Molecular Diagnostics

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Abdullahi Sidi, F., Bingham, V., Craig, S. G., McQuaid, S., James, J., Humphries, M. P., & Salto-Tellez, M. (2020). PD-L1 Multiplex and Quantitative Image Analysis for Molecular Diagnostics. Cancers, 13(1), 29. https://doi.org/10.3390/cancers13010029

PD-L1 Multiplex and Quantitative Image Analysis for Molecular Diagnostics Read More »

Publications

Differences in TCR repertoire and T cell activation underlie the divergent outcomes of antitumor immune responses in tumor-eradicating versus tumor-progressing hosts

Altered Spatial Composition of the Immune Cell Repertoire in Association to CD34+ Blasts in Myelodysplastic Syndromes and Secondary Acute Myeloid Leukemia

Gut-licensed IFNγ + NK cells drive LAMP1 + TRAIL + anti-inflammatory astrocytes

LncRNA DANCR represses Doxorubicin-induced apoptosis through stabilizing MALAT1 expression in colorectal cancer cells

Insulin Receptor Substrate p53 Ameliorates High-Glucose-Induced Activation of NF-κB and Impaired Mobility of HUVECs

The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes

Rova-T Enhances the Anti-Tumor Activity of Anti-PD1 in a Murine Model of Small Cell Lung Cancer with Endogenous Dll3 Expression

Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis

Commensal-Driven Immune Zonation of the Liver Promotes Host Defence

PD-L1 Multiplex and Quantitative Image Analysis for Molecular Diagnostics

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