Boston University, Assistant Professor of Pathology and Laboratory Medicine, Jonathan Cherry, PhD, speaks about how the Opal™ staining platform and the PhenoImager™ HT imaging system (formerly Vectra® Polaris™) enabled him to study the immune profile of diseased brain tissue, a historically challenging tissue type in terms of autofluorescence. Specifically, Dr. Jon Cherry discusses his work studying the evolution of neuronal and glial tau isoforms in chronic traumatic encephalopathy.