Spatial Signature Panel Optimization and Reproducibility to Enable Tumor Immune Profiling
Dr. Cara Haymaker and Dr. Edwin Parra discuss their research work within the Translational Molecular Pathology Immunoprofiling Laboratory (TMP-IL) at MD Anderson Cancer Center focused on the development and reproducibility of an automated nine-colour mIF panel to visualize and characterize the tumor microenvironment (TME). In this webinar, they will present their finding which demonstrate the power of multiplex imaging in exploring cellular phenotype proliferation in the TME and their geographic distribution, and spatial proximity of cell phenotypes related to malignant cells. This research has implications for the potential capability of the data obtained through this methodology for immune profiling FFPE tumor tissues in translational studies.