Webinar

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Multiplex Immunofluorescence (mIF) 101: The Fundamentals

Home Resources Webinars Multiplex Immunofluorescence (mIF) 101: The Fundamentals Webinar Series: November 9, November 30, December 2, December 9, 2021 Join us for this four-part webinar series, featuring members of the JEDI (Joint Effort to Develop Multiplex Immunofluorescence Standards) Council for Multiplex IF/IHC Global Standardization, a multi-disciplinary taskforce comprising globally >30 members of immunologists, oncologists, […]

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Pushing the Frontiers of CAR T-cell Therapy: A Spatial Analysis of Solid Tumors

Research over the years has determined that the spatial context of the TME is key to understanding cancer and improving its treatment. Spatial analysis of the TME reveals the distribution patterns of cell populations and elucidates the communication between cellular components. David Steffin, an assistant professor at Texas Children’s Hospital/Baylor College of Medicine, Houston, will discuss how to use CODEX (CO-Detection by indEXing), a single-cell spatial phenotyping solution, to characterize the microenvironment of various pediatric tumors and to understand the potential interactions that chimeric antigen receptor (CAR) T cells may elicit.

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Location Matters: How Spatial Biology is Driving Discovery

Adding a spatial dimension provides unique and important insights into fundamental questions in biology. The emergence of new cutting-edge techniques, such as high-resolution spectral imaging, lattice light-sheet microscopy, and spatial transcriptomics, allows us to accurately assess the spatial landscape of biological systems at cellular and sub-cellular resolution. Incorporating a spatial element to large-scale analyses of biological processes, small molecule peptides, and disease pathology, has enabled breakthrough discoveries across disciplines in the life sciences. Learn more about spatial technology applied across different topic areas in this exciting Cell Press webinar featuring the work of Jun Huang (University of Chicago), Jun Hee Lee (University of Michigan), and Elizabeth Shank from the (UMass Chan Medical School).

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Diversity Matters: Surveying Cellular Diversity of the Human Kidney Using CODEX

This webinar highlights the power of CODEX multiplex imaging for surveying the cellular diversity of the human kidney, with potential applications in pathology, histology, and building anatomical atlases. Dr. Elizabeth K. Neumann, from Vanderbilt University, describes the use of co-detection by indexing (CODEX) multiplexed immunofluorescence for visualizing 23 antigens within the human kidney. Using CODEX, many of the major cell types and substructures, such as collecting ducts, glomeruli, and thick ascending limb, were visualized within a single tissue section. Of these antibodies, 19 were conjugated in-house, demonstrating the flexibility and utility of this approach for studying the human kidney using traditional antibody markers.

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Spatial Biomarkers in Immuno-Oncology: Recent Developments and Future Directions

Home Resources Webinars Spatial Biomarkers in Immuno-Oncology: Recent Developments and Future Directions Webinar Series: October 6-27, 2021 Recent developments in the study of spatial biomarkers continue to demonstrate the predictive power of this new class of biomarker assays. Watch this four-part webinar series to learn how researchers are pioneering new strategies representing significant milestones that advance spatial

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A Beginner’s Guide to CODEX

In this webinar, we’ll share how phenoptrReports provides powerful, easy-to-use tools to analyze spatial relationships between cellular phenotypes and visualize their relationships overlaid on the tissue, phenotype cells co-expressing markers, determine the quality of your unmixing library, and display results in shareable, easy-to-read data reports. Tips and tricks for getting the most out of your analysis will be reviewed as well.

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CODEX with Seurat: A high-dimensional approach to unlocking spatial insights

Observing cell-cell interactions is critical to understanding causative factors of biological outcomes. As the only benchtop platform capable of multiplexing >40 markers in tissue, CODEX® (rebranded to PhenoCycler™) uniquely enables these observations by assaying tissue biopsies using fluidics, an inverted microscope, oligo-conjugated antibodies, and fluorescent reporters.

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Understanding Spatial Phenotyping: A Webinar Series by Akoya Academy

Home Resources Webinars Understanding Spatial Phenotyping: A Webinar Series by Akoya Academy Webinar Series | August 24 – September 7, 2021 Analyzing the cellular interactions taking place in the tissue microenvironment is critical to understand the processes that drive biological outcomes. Through spatial phenotyping, you can view, characterize, and quantify cells by lineage and variant

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PhenoptrReports: Unlocking the Power of Spatial Biology Analysis

In this webinar, we’ll share how phenoptrReports provides powerful, easy-to-use tools to analyze spatial relationships between cellular phenotypes and visualize their relationships overlaid on the tissue, phenotype cells co-expressing markers, determine the quality of your unmixing library, and display results in shareable, easy-to-read data reports. Tips and tricks for getting the most out of your analysis will be reviewed as well.

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